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Interventions

Every intervention with cost-effectiveness data, grouped by disease area. Badges show which of the four sources each carries. Open any intervention to see its full profile across all countries — signals, cost-effectiveness, evidence, and market.

Looking to compare one intervention’s cost-effectiveness in a specific country? That country-first comparison lives under Tools.

Source:
163 interventions · 25 disease areas
Maternal and newborn health25
Antenatal careWHO-CHOICETufts
Antibiotics for preterm premature rupture of membranes.WHO-CHOICE
Balanced energy-protein supplementation to pregnant women with insecure food availabilityWHO-CHOICETufts
Calcium supplementation in pregnant women for the prevention and management of pre-eclampsia/eclampsiaWHO-CHOICE
Clean cord care (clean birth practices)WHO-CHOICE
Daily iron and folic acid supplementation in pregnant womenWHO-CHOICETufts
Ectopic pregnancy case managementWHO-CHOICE
Facility based management of neonatal infection (sepsis/pneumonia) with injectible (and oral) antibioticsWHO-CHOICE
Folic acid supplementationWHO-CHOICETufts
Full supportive care for premature babiesWHO-CHOICE
Home visits for clean postnatal practicesWHO-CHOICETufts
Hypertensive disease case management in pregnancyWHO-CHOICE
Intermittent presumptive treatment of malariaWHO-CHOICE
Kangaroo mother care (KMC)WHO-CHOICETufts
Management of eclampsia with Magnesium-SulphateWHO-CHOICETufts
Management of maternal sepsisWHO-CHOICE
Management of pre-eclampsia (mild and severe)WHO-CHOICE
Neonatal resuscitationWHO-CHOICETufts
Neonatal sepsis/pneumonia treatmentWHO-CHOICETufts
P5. Skilled delivery + management of complicationsWHO-CHOICE
P7. Case management of newborn complications at referral levelWHO-CHOICE
P8. Community based newborn and child careWHO-CHOICE
Skilled birth attendanceWHO-CHOICETufts
Syphilis detection and treatment in pregnancyWHO-CHOICEDCP3Tufts
Tetanus toxoid vaccinationWHO-CHOICETufts
Mental health16
Antipsychotic medication (newer drugs) plus basic psychosocial treatment for psychosisWHO-CHOICE
Antipsychotic medication (newer drugs) plus intensive psychosocial treatment for psychosisWHO-CHOICE
Antipsychotic medication (older drugs) plus intensive psychosocial treatment for psychosisWHO-CHOICE
Anxiety treatmentWHO-CHOICEDCP3Tufts
Basic psychosocial and antidepressant treatment for first-episode moderate-severe depressionWHO-CHOICEDCP3
Basic psychosocial and antidepressant treatment for moderate-severe anxietyWHO-CHOICE
Bipolar disorder treatmentWHO-CHOICETufts
Depression treatmentWHO-CHOICEDCP3Tufts
Intensive psychosocial and antidepressant treatment for first-episode moderate-severe depressionWHO-CHOICE
Intensive psychosocial and antidepressant treatment for moderate-severe anxietyWHO-CHOICE
Intensive treatment for recurrent moderate-severe depression (episodic)WHO-CHOICE
Intensive treatment for recurrent moderate-severe depression (maintenance)WHO-CHOICEDCP3
Mood-stabilizing medication (newer drugs) plus basic psychosocial treatment for bipolarWHO-CHOICE
Mood-stabilizing medication (newer drugs) plus intensive psychosocial treatment for bipolarWHO-CHOICE
Mood-stabilizing medication (older drugs) plus intensive psychosocial treatment for bipolarWHO-CHOICE
Psychosis treatmentWHO-CHOICEDCP3Tufts
Immunization14
Dengue vaccinationTufts
DPT vaccineWHO-CHOICE
H. influenzae b vaccineWHO-CHOICE
Hepatitis B vaccination and treatmentTufts
Measles vaccineWHO-CHOICETufts
Meningococcal vaccinationTufts
Oral cholera vaccinationTufts
P11.Routine EPI + Rotavirus, PneumococcalWHO-CHOICE
Pentavalent vaccineGiveWellWHO-CHOICETufts
Pneumococcal vaccineWHO-CHOICEDCP3Tufts
Polio vaccination (OPV/IPV)Tufts
Rotavirus vaccineWHO-CHOICEDCP3Tufts
Routine EPIWHO-CHOICE
Typhoid vaccinationTufts
Cardiovascular disease13
Blood pressure lowering treatment for those with SBP > 140 mmHg and total CVD risk < 20%WHO-CHOICE
Blood pressure lowering treatment for those with SBP > 140 mmHg and total CVD risk < 30%WHO-CHOICE
Blood pressure lowering treatment for those with SBP > 160 mmHg and total CVD risk < 20%WHO-CHOICE
Blood pressure treatmentWHO-CHOICEDCP3Tufts
Cholesterol lowering treatment for those with Chol > 6 mmol/L and total CVD risk < 20%WHO-CHOICE
Cholesterol lowering treatment for those with Chol > 6 mmol/L and total CVD risk < 30%WHO-CHOICEDCP3
Cholesterol lowering treatment for those with Chol > 8 mmol/L and total CVD risk < 20%WHO-CHOICE
Cholesterol lowering treatment for those with Chol > 8 mmol/L and total CVD risk < 30%WHO-CHOICEDCP3Tufts
Combination therapy for prevention of CVD in those with 20%+ riskWHO-CHOICE
Combination treatment of new cases of acute myocardial infarctionWHO-CHOICEDCP3
Combination treatment of new cases of strokeWHO-CHOICE
CVD combination therapyWHO-CHOICETufts
Heart attack treatment (aspirin)WHO-CHOICEDCP3Tufts
Malaria11
As CMU_CMS_ITN but treatment seeking fever cases RDT testedWHO-CHOICE
Malaria bed nets (ITN)GiveWellDCP3
Management of severe casesWHO-CHOICE
Management of severe casesWHO-CHOICEDCP3
Management of severe cases + Insecticide-treated bed netsWHO-CHOICE
Management of suspected uncomplicated cases + Management of severe casesWHO-CHOICE
Management of suspected uncomplicated cases + Management of severe casesDCP3
Management of suspected uncomplicated cases + Management of severe cases + Insecticide-treated bed netsWHO-CHOICE
Management of suspected uncomplicated cases + Management of severe cases + Insecticide-treated bed netsWHO-CHOICE
Management of suspected uncomplicated cases + Management of severe cases + Insecticide-treated bed nets + Malaria vaccine with RTS,SWHO-CHOICE
Seasonal malaria prevention (SMC)GiveWell
HIV/AIDS9
ART5 + MMCO + FSW + PWID + MSM + YFI + STI management + VMMCWHO-CHOICE
Female sex workers and clientsWHO-CHOICETufts
HIV testing + ART + PMTCTWHO-CHOICE
HIV treatment (ART)Tufts
Interventions targeting men who have sex with menTufts
Mass media communication designed to increase demand and improve use of condoms, and condom provisionWHO-CHOICETufts
People who inject drugs community outreach and peer educationTufts
TasP + MMCO + FSW + PWID + MSM + YFI + STI management + VMMCWHO-CHOICE
Voluntary medical male circumcisionWHO-CHOICEDCP3Tufts
COPD7
Antibiotics for COPD exacerbationWHO-CHOICE
Inhaled salbutamol for COPDWHO-CHOICE
Ipratropium inhaler for COPDWHO-CHOICE
Low-dose oral theophylline for COPDWHO-CHOICE
Oral prednisolone for COPD exacerbationWHO-CHOICE
Oxygen therapy for COPDWHO-CHOICE
Smoking cessation brief intervention by a GPWHO-CHOICE
Tuberculosis7
B1 + ART prioritization + Preventive therapy + Preventive therapy for childrenWHO-CHOICE
B1 + Preventive therapyTufts
B1 + Preventive therapy for childrenWHO-CHOICE
B2 + ART prioritization for TB casesWHO-CHOICE
TB detection (Xpert)WHO-CHOICEDCP3Tufts
TB treatment (DOTS)WHO-CHOICEDCP3Tufts
TB treatment + ART prioritizationWHO-CHOICE
Cervical cancer6
Basic palliative care for cervical cancerWHO-CHOICE
Cervical cancer screening (HPV test)WHO-CHOICETufts
Diagnosis and treatment of cervical cancer stages I and IIWHO-CHOICE
HPV vaccinationWHO-CHOICEDCP3Tufts
Prevention of cervical cancer through screening with PAP smearWHO-CHOICE
Prevention of cervical cancer through screening with VIAWHO-CHOICE
Child health6
Antibiotics for treatment of dysenteryWHO-CHOICE
Childhood pneumonia treatmentWHO-CHOICETufts
Integrated child management (IMCI)WHO-CHOICE
ORS/ZincGiveWellWHO-CHOICETufts
Pneumonia treatment (facility)WHO-CHOICE
Respiratory syncytial virus (RSV) preventionTufts
Family planning6
Family planningWHO-CHOICEDCP3Tufts
Post-abortion careWHO-CHOICE
Preventing unplanned pregnancyWHO-CHOICE
Safe abortion servicesWHO-CHOICE
Skilled delivery + complications + FPWHO-CHOICE
Skilled delivery + FPWHO-CHOICE
Nutrition6
Breastfeeding promotionWHO-CHOICETufts
Food fortification (wheat, oil, sugar with iron, folic acid, vitamin A, zinc)Tufts
P9. Infant and young child feedingWHO-CHOICE
Promotion of complementary feedingWHO-CHOICE
Severe acute malnutrition treatmentWHO-CHOICETufts
Vitamin A supplementationGiveWellWHO-CHOICETufts
Asthma5
Asthma treatment (beclomethasone)WHO-CHOICE
High dose inhaled beclomethasone plus SABAWHO-CHOICE
Inhaled short acting beta agonist (SABA) for intermittent asthmaWHO-CHOICE
Oral prednisolone plus theophylline plus high dose inhaled beclomethasone plus SABAWHO-CHOICE
Theophylline plus high dose inhaled beclomethasone plus SABAWHO-CHOICE
Tobacco control5
Enforce bans on tobacco advertising, promotion and sponsorshipWHO-CHOICEDCP3
Mass media campaigns for smoking preventionDCP3
Offer help to quit tobacco useWHO-CHOICETufts
Protect people from tobacco smokeDCP3WHO-CHOICETufts
Raise taxes on tobaccoDCP3Tufts
Unhealthy diet5
Front-of-pack labelling for salt reductionWHO-CHOICE
Mass media campaign for salt reductionDCP3
Salt reduction in community-based eating spacesWHO-CHOICE
Trans fat elimination through legislationWHO-CHOICE
Voluntary industry reformulation for salt reductionTufts
Alcohol control4
Alcohol excise taxDCP3Tufts
Alcohol harm interventionTufts
Enforcement of drink-driving laws via sobriety checkpointsDCP3
Restrictions on marketing of alcoholic beveragesDCP3
Diabetes4
Intensive glycaemic controlWHO-CHOICE
Neuropathy screening and preventive foot careWHO-CHOICE
Retinopathy screening and photocoagulationWHO-CHOICEDCP3Tufts
Standard glycaemic controlWHO-CHOICETufts
Breast cancer3
Basic palliative care for breast cancerWHO-CHOICE
Breast cancer screeningWHO-CHOICETufts
Diagnosis and treatment of breast cancer stages I and IIWHO-CHOICEDCP3
WASH3
Household water treatment (chlorination, filtration, safe storage)DCP3Tufts
Hygiene promotion (handwashing with soap, community hygiene education)Tufts
Improved sanitation (latrines, sewerage, fecal sludge management)DCP3Tufts
Colorectal cancer2
Basic palliative care for colorectal cancerWHO-CHOICE
Diagnosis and treatment of colorectal cancer stages I and IIWHO-CHOICE
Epilepsy2
Antiepileptic medication (newer drugs) plus basic psychosocial treatment for epilepsyWHO-CHOICE
Epilepsy treatmentWHO-CHOICEDCP3Tufts
Eye health1
Cataract surgery and eye screeningTuftsDCP3
Neglected tropical diseases1
DewormingTufts
Physical inactivity1
Physical activity counselling as brief intervention in primary careWHO-CHOICEDCP3
Poverty reduction1
Cash transfersTufts